• jeudi 26 janvier 2017

Séminaire exceptionnel Namisceb : Collagen-based extra-cellular matrices – the underestimated role of water

11h00 // Salle de séminaire du LIPhy

140 Avenue de la Physique 38402 Saint Martin d’Hères

Prof. Peter Fratzl (Max Planck Institute of Colloids and Interfaces, Potsdam-Golm, Germany)

Collagen is the main organic component of many tissues in our body, including tendons, bone and dentin. The multi-scale structure of these tissues provides exceptional mechanical properties that combine stiffness with resilience or toughness. The talk will briefly review the current knowledge about the multi-scale structure of collagen in tendon and bone, in relation to their mechanical behavior. Recent data also show that collagen may contract by the action of osmotic stresses and provide pretension in extracellular tissues that compress mineral in dentin and bone. This indicates that collagen is not just a passive scaffold molecule in the extracellular matrix but that it likely plays an active mechanical role in establishing pre-tension in a variety of extracellular tissues.

Contact : aurelie.dupont@univ-grenoble-alpes.fr


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